From the Wikipedia entry on
Tithonus:
Eos kidnapped Ganymede and Tithonus, both from the royal house of Troy, to be her lovers. The mytheme of the goddess's immortal lover is an archaic one; when a role for Zeus was inserted, a bitter new twist appeared: According to the Homeric Hymn to Aphrodite, when Eos asked Zeus for Tithonus to be immortal, she forgot to ask for eternal youth (218-38). Tithonus indeed lived forever, "but when loathsome old age pressed full upon him, and he could not move nor lift his limbs, this seemed to her in her heart the best counsel: she laid him in a room and put to the shining doors. There he babbles endlessly, and no more has strength at all, such as once he had in his supple limbs." (Homeric Hymn to Aphrodite)
From Lovecraft's "The Whisperer in Darkness":
Just what the real situation was, I could not guess; but common sense told me that the safest thing was to find out as much as possible before arousing anybody. Regaining the hall, I silently closed and latched the living-room door after me; thereby lessening the chances of awakening Noyes. I now cautiously entered the dark study, where I expected to find Akeley, whether asleep or awake, in the great corner chair which was evidently his favorite resting-place. As I advanced, the beams of my flashlight caught the great centre-table, revealing one of the hellish cylinders with sight and hearing machines attached, and with a speech machine standing close by, ready to be connected at any moment. This, I reflected, must be the encased brain I had heard talking during the frightful conference; and for a second I had a perverse impulse to attach the speech machine and see what it would say.
It must, I thought, be conscious of my presence even now; since the sight and hearing attachments could not fail to disclose the rays of my flashlight and the faint creaking of the floor beneath my feet. But in the end I did not dare meddle with the thing. I idly saw that it was the fresh shiny cylinder with Akeley’s name on it, which I had noticed on the shelf earlier in the evening and which my host had told me not to bother. Looking back at that moment, I can only regret my timidity and wish that I had boldly caused the apparatus to speak. God knows what mysteries and horrible doubts and questions of identity it might have cleared up! But then, it may be merciful that I let it alone.
In the latter story, these jars do indeed hold human brains, which can see and hear when connected to sensory apparatus, and can speak when connected to voice synthesizers...which means that it's easy to let one sense the world but unable to respond to it, and also to lock it away within its own thoughts, indefinitely.
For some reason these motifs of the trapped, isolated mind have always held a particular horror for me,
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